Mental Disorder Associated With Smoking

Somebody has to do a study on the ridiculous research techniques and wasteful spending habits of academia. Now we get this piece of soon to be trivia from the odd files of dubious science.

Comorbidity of psychiatric and substance use disorders represents a significant complication in the clinical course of both disorders. Bipolar Disorder (BD) is a psychiatric disorder characterized by severe mood swings, ranging from mania to depression, and up to a 70% rate of comorbid Tobacco Use Disorder (TUD).

Yep, you heard right, ‘Tobacco Use Disorder’.

Just think of what an evil doer Sir Walter Raleigh must have been for having delivered tobacco smoking from the native populations of the New World to what was then regarded as civilized society. Little did he know he was actually spreading disease far and wide.

America’s one cash crop way back when and now linked to, uh, mental disease.

Connect the gene for this disorder with the gene for ‘bipolar disorder’, a disorder whose rate has climbed 40 fold in recent times due to the manipulation of a certain Harvard psychiatrist, Dr. Joseph Biederman, recently under investigation by Senator Grassley and his Senate committee for taking unreported kickbacks from drug companies, and you have a case of high farcical tragic-comedy.

Results: We estimate risk for TUD among BD patients at 2.4 times that of the general population.

I know…cancer. Everybody else is quitting, but those whose nerves demand some kind of extra stimulation.

They’ve even identified 3 genes they are associating with the highs and lows of ‘bipolar disorder’ and, cough (excuse me, no smokers hack, just the mock reflex), ‘Tobacco Use Disorder’.

We found three candidate genes associated with both BD and TUD (COMT, SLC6A3, and SLC6A4) and commonality analysis suggests that these genes interact in predisposing psychiatric and substance use disorders. We identified a 69 gene network that influences neurotransmitter signaling and shows significant over-representation of genes associated with BD and TUD, as well as genes differentially expressed with exposure to tobacco smoke.

I would suggest somebody needs to take a serious look at the genes of the hare-brained researchers who conduct research based on such wild and bizarre hypotheses. Alas, but I also suspect self-control is rabidly being drained from the gene pool.