More bad science: attributing damage to “disease” that could be due to drug

Why must doctors turn a blind eye every time a study is conducted attributing brain volume loss, and structural change, to “schizophrenia”? You have proven nothing if you don’t factor in the little matter of psychiatric drug usage. These drugs are known, from both animal and human studies, to effect the brain in negative ways. Some of these negative effects involve brain mass loss and structural change.

Biological psychiatry is chock full of junk science, and here’s just another example, from News-Medical.Net, Increased cortical thinning in schizophrenia patients.

The team studied 20 patients with schizophrenia, aged 17‑65 years, and 20 age- and gender-matched mentally healthy individuals (controls) without a history of substance abuse (moderate or severe) or dependence (any type) during the past 6 months.

The subjects of this research were given an initial MRI brain scan followed after two years by another MRI scan.

Problem. This study is contrasting “patients with schizophrenia” to “mentally healthy individuals”. What this study doesn’t seem to be doing is factoring in psychiatric drugs. We know that psychiatric drugs do funny things to the brain. You need to further divide this study into two more groups, “schizophrenia” patients treated with neuroleptic drugs and “schizophrenia” patients treated without neuroleptic drugs, before you can say that the thinning and volume loss isn’t the result of treatment rather than of “disease”.

Neuroleptic drugs in animal studies cause brain tissue loss. There is little indication that these drugs don’t cause tissue loss in that animal species homo sapiens as well.

The researchers found that schizophrenia patients showed significantly greater cortical thinning than controls over the study period, particularly in the middle frontal gyrus, the superior temporal gyrus, and the middle temporal gyrus.

This cortical thinning occurs after 2 years on neuroleptic drugs I take it.

“Overall it appears that ongoing abnormalities in the cerebral cortex continue after initial onset of schizophrenia, particularly the lateral aspects of frontal and temporal regions, and do not relate to neuropsychological or clinical measures over time,” [Derin] Cobia and team conclude.

Or after the initial onset of the neuroleptic drug treatment that follows immediately on the heels of diagnosis.

You can’t do real science and be so timorous with regard to your subjects. One can only assume that the researchers are neglecting to factor in psychiatric drugs out of bias and wishful thinking, if they aren‘t simply trying to be deceptive because they know better. I don’t know who they think they are deceiving, but if they haven’t factored in psychiatric drugs, they aren’t deceiving me. Neglecting to determine whether damage is caused by “disease”, or by drug, is not being sufficiently thorough in your investigations. If these researchers are trying to deceive people, real research remains to be done on the subject because it hasn‘t been done in this study

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